Cyclebase 3.0

Cell-cycle regulation database

PIL1 [YGR086C]

Sphingolipid long chain base-responsive protein PIL1; Eisosome core component; eisosomes are large immobile cell cortex structures associated with endocytosis; detected in phosphorylated state in mitochondria; phosphorylated on Thr233 upon Pkc1p hyperactivation in a Slt2p MAPK-dependent fashion; null mutant shows activation of Pkc1p/Ypk1p stress resistance pathways; member of BAR domain family; protein increases in abundance and relocalizes from plasma membrane to cytoplasm upon DNA replication stress

Synonyms:  PIL1,  PIL1p,  P53252,  P53252p,  YGR086C ...

Linkouts:  STRING  UniProt