Cyclebase 3.0

Cell-cycle regulation database

MPT5 [YGL178W]

Pumilio homology domain family member 5; mRNA-binding protein of the PUF family; binds to specific mRNAs, often in the 3' UTR; has broad specificity and binds to more than 1000 mRNAs (16% of the transcriptome); recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity

Synonyms:  MPT5,  MPT5p,  P39016,  BIC834,  HTR1 ...

Linkouts:  STRING  UniProt