Cyclebase 3.0

Cell-cycle regulation database

SNT2 [YGL131C]

Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitination, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress

Synonyms:  SNT2,  SNT2p,  P53127,  G2850,  P53127p ...

Linkouts:  STRING  UniProt