Cyclebase 3.0

Cell-cycle regulation database

NUP145 [YGL092W]

Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98

Synonyms:  NUP145,  NUP145p,  P49687,  P49687p,  RAT10 ...

Linkouts:  STRING  UniProt