Cyclebase 3.0

Cell-cycle regulation database

ERG26 [YGL001C]

Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; human homolog NSDHL implicated in CK syndrome, and can complement yeast null mutant; molecular target of natural product and antifungal compound FR171456; Belongs to the 3-beta-HSD family.

Synonyms:  ERG26,  ERG26p,  P53199,  P53199p,  YGL001C ...

Linkouts:  STRING  UniProt