Cyclebase 3.0

Cell-cycle regulation database

HAC1 [YFL031W]

Transcriptional activator HAC1; Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis; two functional forms of Hac1p are produced; translation initiation is repressed under non-stress conditions; protein abundance increases in response to DNA replication stress

Synonyms:  HAC1,  HAC1p,  P41546,  ERN4,  IRE15 ...

Linkouts:  STRING  UniProt