Cyclebase 3.0

Cell-cycle regulation database

RAD4 [YER162C]

Protein that recognizes and binds damaged DNA (with Rad23p) during NER; subunit of Nuclear Excision Repair Factor 2 (NEF2); also involved, with Rad23p, in turnover of ubiquitylated proteins; Rad4p-Rad23p heterodimer binds to promoters of DNA damage response genes to repress their transcription in the absence of DNA damage; NER stands for nucleotide excision repair; Belongs to the XPC family.

Synonyms:  RAD4,  RAD4p,  P14736,  P14736p,  YER162C ...

Linkouts:  STRING  UniProt