DOT6 [YER088C]
Disrupter of telomere silencing protein 6; Protein involved in rRNA and ribosome biogenesis; activated in stochastic pulses of nuclear localization; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation; relative distribution to the nucleus increases upon DNA replication stress; Belongs to the DOT6 family.
Synonyms: DOT6, DOT6p, P40059, P40059p, PBF2 ...