Cyclebase 3.0

Cell-cycle regulation database

YEN1 [YER041W]

Holliday junction resolvase; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1; similar to S. cerevisiae endonuclease Rth1p

Synonyms:  YEN1,  YEN1p,  P40028,  P40028p,  YER041W ...

Linkouts:  STRING  UniProt