Cyclebase 3.0

Cell-cycle regulation database

PHM8 [YER037W]

Phosphate metabolism protein 8; Lysophosphatidic acid (LPA) phosphatase, nucleotidase; principle and physiological nucleotidase working on GMP, UMP and CMP; involved in LPA hydrolysis in response to phosphate starvation and ribose salvage pathway; phosphatase activity is soluble and Mg2+ dependent; expression is induced by low phosphate levels and by inactivation of Pho85p; repressed by Gcn4p under normal conditions; PHM8 has a paralog, SDT1, that arose from the whole genome duplication

Synonyms:  PHM8,  PHM8p,  P40025,  P40025p,  YER037W ...

Linkouts:  STRING  UniProt