Cyclebase 3.0

Cell-cycle regulation database

SRB4 [YER022W]

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for basal RNA polymerase II transcription; homozygosity of the human MED17 L371P mutation is associated with infantile cerebral and cerebellar atrophy with poor myelination

Synonyms:  SRB4,  SRB4p,  P32569,  MED17,  P32569p ...

Linkouts:  STRING  UniProt