Cyclebase 3.0

Cell-cycle regulation database

NHX1 [YDR456W]

Endosomal/prevacuolar sodium/hydrogen exchanger; Na+/H+ and K+/H+ exchanger; required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; ortholog of human NHE9, which is linked to autism; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Synonyms:  NHX1,  NHX1p,  Q04121,  D9461.40,  NHA2 ...

Linkouts:  STRING  UniProt