Cyclebase 3.0

Cell-cycle regulation database

TSA2 [YDR453C]

Thiol-specific antioxidant protein 2; Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants; protein abundance increases in response to DNA replication stress; TSA2 has a paralog, TSA1, that arose from the whole genome duplication; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

Synonyms:  TSA2,  TSA2p,  Q04120,  D9461.38,  Q04120p ...

Linkouts:  STRING  UniProt