Cyclebase 3.0

Cell-cycle regulation database

RAD30 [YDR419W]

Radiation-sensitive protein 30; DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV

Synonyms:  RAD30,  RAD30p,  Q04049,  DBH1,  Q04049p ...

Linkouts:  STRING  UniProt