Cyclebase 3.0

Cell-cycle regulation database

UPC2 [YDR213W]

Mannoprotein regulation by oxygen protein 4; Sterol regulatory element binding protein; induces sterol biosynthetic genes, upon sterol depletion; acts as a sterol sensor, binding ergosterol in sterol rich conditions; relocates from intracellular membranes to perinuclear foci upon sterol depletion; redundant activator of filamentation with ECM22, up-regulating the expression of filamentous growth genes; contains a Zn[2]-Cys[6] binuclear cluster; UPC2 has a paralog, ECM22, that arose from the whole genome duplication

Synonyms:  UPC2,  UPC2p,  Q12151,  MOX4,  Q12151p ...

Linkouts:  STRING  UniProt