Cyclebase 3.0

Cell-cycle regulation database

GCD6 [YDR211W]

Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress; Belongs to the eIF-2B gamma/epsilon subunits family.

Synonyms:  GCD6,  GCD6p,  P32501,  P32501p,  TIF225 ...

Linkouts:  STRING  UniProt