Cyclebase 3.0

Cell-cycle regulation database

PPH3 [YDR075W]

Catalytic subunit of protein phosphatase PP4 complex; Pph3p and Psy2p form active complex, Psy4p may provide substrate specificity; regulates recovery from the DNA damage checkpoint, the gene conversion- and single-strand annealing-mediated pathways of meiotic double-strand break repair and efficient Non-Homologous End-Joining (NHEJ) pathway; involved in activation of Gln3p to alleviate nitrogen catabolite repression; Pph3p and Psy2p localize to foci on meiotic chromosomes; Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.

Synonyms:  PPH3,  PPH3p,  P32345,  D4421,  P32345p ...

Linkouts:  STRING  UniProt