Cyclebase 3.0

Cell-cycle regulation database

DBF4 [YDR052C]

Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation

Synonyms:  DBF4,  DBF4p,  P32325,  D4205,  DNA52 ...

Linkouts:  STRING  UniProt