Cyclebase 3.0

Cell-cycle regulation database

MAF1 [YDR005C]

Highly conserved negative regulator of RNA polymerase III; involved in tRNA processing and stability; inhibits tRNA degradation via rapid tRNA decay (RTD) pathway; binds N-terminal domain of Rpc160p subunit of Pol III to prevent closed-complex formation; regulated by phosphorylation mediated by TORC1, protein kinase A, Sch9p, casein kinase 2; localizes to cytoplasm during vegetative growth and translocates to nucleus and nucleolus under stress conditions

Synonyms:  MAF1,  MAF1p,  P41910,  P41910p,  YD8119.11C ...

Linkouts:  STRING  UniProt