Cyclebase 3.0

Cell-cycle regulation database

LYS20 [YDL182W]

Homocitrate synthase isozyme and functions in DNA repair; catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; LYS20 has a paralog, LYS21, that arose from the whole genome duplication; Belongs to the alpha-IPM synthase/homocitrate synthase family.

Synonyms:  LYS20,  LYS20p,  P48570,  D1298,  P48570p ...

Linkouts:  STRING  UniProt