Cyclebase 3.0

Cell-cycle regulation database

SCM3 [YDL139C]

Suppressor of chromosome missegregation protein 3; Nonhistone component of centromeric chromatin; binds to histone H3 variant, Cse4p, and recruits it to centromeres; involved in the assembly and maintenance of Cse4-H4 at centromeres; required for kinetochore assembly and G2/M progression; may protect Cse4p from ubiquitination; homolog of mammalian HJURP

Synonyms:  SCM3,  SCM3p,  Q12334,  D2155,  Q12334p ...

Linkouts:  STRING  UniProt