CDC53 [YDL132W]
E3 ubiquitin ligase complex SCF subunit CDC53; Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant
Synonyms: CDC53, CDC53p, Q12018, D2190, Q12018p ...