HEM25 [YDL119C]
Solute carrier family 25 member 38 homolog; Mitochondrial glycine transporter; required for the transport of glycine into mitochondria for initiation of heme biosynthesis, with YMC1 acting as a secondary transporter; homolog of human SLC25A38, a mitochondrial glycine transporter associated with nonsyndromic autosomal recessive congenital sideroblastic anemia; human SLC25A38 can complement the heme deficiency associated with the null mutant; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
Synonyms: HEM25, HEM25p, YDL119C, Q07534, YDL119Cp ...