Cyclebase 3.0

Cell-cycle regulation database

ABP1 [YCR088W]

Actin-binding protein of the cortical actin cytoskeleton; important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization; inhibits barbed-end actin filament elongation; phosphorylation within its Proline-Rich Regio, mediated by Cdc28p and Pho85p, protects Abp1p from proteolysis mediated by its own PEST sequences; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa)

Synonyms:  ABP1,  ABP1p,  P15891,  P15891p,  YCR088W ...

Linkouts:  STRING  UniProt