Cyclebase 3.0

Cell-cycle regulation database

PAT1 [YCR077C]

Decapping activator and translational repressor PAT1; Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; binds to mRNAs under glucose starvation, most often in the 3' UTR; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress; phosphorylation by PKA inhibits P body foci formation; Belongs to the PAT1 family.

Synonyms:  PAT1,  PAT1p,  P25644,  MRT1,  P25644p ...

Linkouts:  STRING  UniProt