Cyclebase 3.0

Cell-cycle regulation database

ATG15 [YCR068W]

Cytoplasm to vacuole targeting protein 17; Phospholipase; preferentially hydrolyses phosphatidylserine, with minor activity against cardiolipin and phosphatidylethanolamine; required for lysis of autophagic and CVT bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway; required for the maintenance of lipid droplet quantity after the diauxic shift; regulates lipolysis; expression regulated by Yap1p during autophagy; Belongs to the AB hydrolase superfamily. Lipase family.

Synonyms:  ATG15,  ATG15p,  P25641,  AUT5,  CVT17 ...

Linkouts:  STRING  UniProt