Cyclebase 3.0

Cell-cycle regulation database

RAD18 [YCR066W]

Postreplication repair E3 ubiquitin-protein ligase RAD18; E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair; SUMO-targeted ubiquitin ligase (STUbl) that contains a SUMO-interacting motif (SIM) which stimulates its ubiquitin ligase activity towards the sumoylated form of PCNA

Synonyms:  RAD18,  RAD18p,  P10862,  P10862p,  YCR066W ...

Linkouts:  STRING  UniProt