Cyclebase 3.0

Cell-cycle regulation database

CIT2 [YCR005C]

Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate; expression is controlled by Rtg1p and Rtg2p transcription factors; SCF-Ucc1 regulates level of Cit2p to maintain citrate homeostasis; oxaloacetate-dependent positive feedback loop inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1, that arose from the whole genome duplication

Synonyms:  CIT2,  CIT2p,  P08679,  P08679p,  YCR005C ...

Linkouts:  STRING  UniProt