Cyclebase 3.0

Cell-cycle regulation database

APA1 [YCL050C]

Protein APA1; AP4A phosphorylase; bifunctional diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase and ADP sulfurylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; catalyzes phosphorolysis of dinucleoside oligophosphates, cleaving substrates' alpha/beta-anhydride bond and introducing Pi into the beta-position of the corresponding NDP formed; protein abundance increases under DNA replication stress; APA1 has a paralog, APA2, that arose from the whole genome duplication; Belongs to the ATP adenylyltransferase family.

Synonyms:  APA1,  APA1p,  P16550,  DTP,  P16550p ...

Linkouts:  STRING  UniProt