Cyclebase 3.0

Cell-cycle regulation database

COS2 [YBR302C]

Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins

Synonyms:  COS2,  COS2p,  L000004716,  S000000506,  YBR302C ...

Linkouts:  STRING