Cyclebase 3.0

Cell-cycle regulation database

PCH2 [YBR186W]

Pachytene checkpoint protein 2; Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation

Synonyms:  PCH2,  PCH2p,  P38126,  P38126p,  YBR1308 ...

Linkouts:  STRING  UniProt