Cyclebase 3.0

Cell-cycle regulation database

CKS1 [YBR135W]

Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant

Synonyms:  CKS1,  CKS1p,  P20486,  P20486p,  YBR1011 ...

Linkouts:  STRING  UniProt