Cyclebase 3.0

Cell-cycle regulation database

ATG8 [YBL078C]

Autophagy-related ubiquitin-like modifier ATG8; Component of autophagosomes and Cvt vesicles; regulator of Atg1p, targets it to autophagosomes; binds the Atg1p-Atg13p complex, triggering its vacuolar degradation; unique ubiquitin-like protein whose conjugation target is lipid phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation; deconjugation of Atg8p-PE is required for efficient autophagosome biogenesis

Synonyms:  ATG8,  ATG8p,  P38182,  APG8,  AUT7 ...

Linkouts:  STRING  UniProt