Cyclebase 3.0

Cell-cycle regulation database

EDE1 [YBL047C]

EH domain-containing and endocytosis protein 1; Scaffold protein involved in the formation of early endocytic sites; putative regulator of cytokinesis; homo-oligomerization is required for localization to and organization of endocytic sites; has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death; homolog of mammalian Eps15; Belongs to the VDP/USO1/EDE1 family.

Synonyms:  EDE1,  EDE1p,  P34216,  BUD15,  P34216p ...

Linkouts:  STRING  UniProt