Cyclebase 3.0

Cell-cycle regulation database

GPB2 [YAL056W]

Guanine nucleotide-binding protein subunit beta 2; Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication

Synonyms:  GPB2,  GPB2p,  P39717,  KRH1,  P39717p ...

Linkouts:  STRING  UniProt