Set1 [SPCC306.04c.1]
Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the Set1 complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Methylation promotes maintenance of active chromatin states at euchromatic chromosomal domains and is present throughout the cell cycle. Plays a role in telomere maintenance and DNA repair in an ATM kinase rad3-dependent pathway. Required for efficient telomeric and centromeric silencing; Belongs to the class V-like SAM-binding methyltransferase superfamily.
Synonyms: set1, set1p, SET1_SCHPO; SET1_SCHPO; SET1_SCHPO, kmt2, SPCC306.04c ...
Linkouts: STRING