Cyclebase 3.0

Cell-cycle regulation database

Bub1 [SPCC1322.12c.1]

Checkpoint serine/threonine-protein kinase bub1; Involved in cell cycle checkpoint enforcement. Acts to stabilize the spindle during mitosis. Required for the correct localization of bub3 and mad3 to the kinetochore. Appears to have a role in chromosome segregation. Catalyzes the phosphorylation of bub3.

Synonyms:  bub1,  bub1p,  BUB1_SCHPO; BUB1_SCHPO,  SPCC1322.12c,  14730319 ...

Linkouts:  STRING