Rik1 [SPCC11E10.08.1]
Chromatin modification-related protein rik1; Component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci. Rik1 has also a function in meiotic telomere clustering.
Synonyms: rik1, rik1p, RIK1_SCHPO; RIK1_SCHPO, SPCC11E10.08, 16040243 ...
Linkouts: STRING