Pob3 [SPBC609.05.1]
Facilitates chromatin transcription complex subunit pob3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity); Belongs to the SSRP1 family.
Synonyms: pob3, pob3p, POB3_SCHPO; POB3_SCHPO, SPBC609.05, 25/25F06 ...
Linkouts: STRING