Clr4 [SPBC428.08c.1]
Histone-lysine N-methyltransferase, H3 lysine-9 specific; Histone methyltransferase. Catalytic component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
Synonyms: clr4, clr4p, CLR4_SCHPO; CLR4_SCHPO; CLR4_SCHPO, kmt1, SPBC428.08c ...
Linkouts: STRING