Csn1 [SPBC215.03c.1]
COP9/signalosome complex subunit Csn1; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity). Required, indirectly, for activation of ribonucleotide reductase through the degradation of the protein spd1, thereby supplying deoxyribonucleotides for DNA replication and repair; Belongs to the CSN1 family.
Synonyms: csn1, csn1p, CSN1_SCHPO; CSN1_SCHPO, SPBC215.03c, 23/23C05 ...
Linkouts: STRING