Mcm6 [SPBC211.04c.1]
DNA replication licensing factor mcm6; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity).
Synonyms: mcm6, mcm6p, MCM6_SCHPO; MCM6_SCHPO; MCM6_SCHPO, mis5, SPBC211.04c ...
Linkouts: STRING