Cyclebase 3.0

Cell-cycle regulation database

Myo1 [SPBC146.13c.1]

Class I unconventional myosin; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Contributes to proper septation by transporting vesicles containing septal material to the division site and is involved in the formation of sterol-rich membrane domains at the cell division site. Required also for mating.

Synonyms:  myo1,  myo1p,  MYO1_SCHPO; MYO1_SCHPO,  SPBC146.13c,  11076964 ...

Linkouts:  STRING