Cut4 [SPBC106.09.1]
Anaphase-promoting complex subunit Apc1; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Mutations to this protein prevent the exit from mitosis.
Synonyms: cut4, APC1_SCHPO; APC1_SCHPO; APC1_SCHPO, cut4p, apc1, SPBC106.09 ...
Linkouts: STRING