Mcl1 [SPAPB1E7.02c.1]
DNA polymerase alpha accessory factor Mcl1; Has a role in regulating DNA replication complexes. Acts as a regulator of post DNA replication initiation. Associates with chromatin during G1 and S phases of mitosis. Required for the transcriptional repression of the outer repeats of the centromeric region. Acts as a polymerase alpha replication accessory factor and is important for S-phase DNA damage survival. Plays a role in lagging-strand synthesis and Ozaki fragment processing, in addition to DNA repair.
Synonyms: mcl1, mcl1p, MCL1_SCHPO; MCL1_SCHPO; MCL1_SCHPO, slr3, SPAPB1E7.02c ...
Linkouts: STRING