Cyclebase 3.0

Cell-cycle regulation database

Hsp90 [SPAC926.04c.1]

Heat shock protein 90 homolog; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Interacts with the wee1 protein kinase; which requires swo1 for its activation; Belongs to the heat shock protein 90 family.

Synonyms:  hsp90,  hsp90p,  HSP90_SCHPO; HSP90_SCHPO; HSP90_SCHPO,  SPAC926.04c,  swo1 ...

Linkouts:  STRING