Cyclebase 3.0

Cell-cycle regulation database

Acp2 [SPAC631.01c.1]

F-actin capping protein beta subunit Acp2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Competes with formin cdc12 for attachment to the actin filaments barbed ends. Slowly replaces cdc12 on the barbed ends in preparation for filament disassembly during contractile ring constriction.

Synonyms:  acp2,  acp2p,  CAPZB_SCHPO; CAPZB_SCHPO,  SPAC631.01c,  2543390 ...

Linkouts:  STRING