Lsd2 [SPAC23E2.02.1]
Histone demethylase SWIRM2 (predicted); Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role; Belongs to the flavin monoamine oxidase family.
Synonyms: lsd2, lsd2p, LSD2_SCHPO; LSD2_SCHPO; LSD2_SCHPO; LSD2_SCHPO, saf140, SPAC23E2.02 ...
Linkouts: STRING