Cyclebase 3.0

Cell-cycle regulation database

Rad4 [SPAC23C4.18c.1]

S-M checkpoint control protein rad4; Essential component for DNA replication and also the checkpoint control system which couples S and M phases. May directly or indirectly interact with chromatin proteins to form the complex required for the initiation and/or progression of DNA synthesis. Interacts simultaneously with both 'Thr-187' phosphorylation sites in a crb2 dimer for establishing the DNA checkpoint.

Synonyms:  rad4,  rad4p,  RAD4_SCHPO; RAD4_SCHPO; RAD4_SCHPO,  cut5,  SPAC23C4.18c ...

Linkouts:  STRING