TAZ1 [YPR140W]
1-acylglycerophosphocholine O-acyltransferase; Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant
Synonyms: TAZ1, TAZ1p, Q06510, Q06510p, YPR140W ...